New PDF release: Advances in Breast Cancer Management

By Melody A. Cobleigh M.D. (auth.), William J. Gradishar M.D., William C. Wood M.D. (eds.)

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Oncology (Huntingt) 10:991-1002, 1996. Fowble B: Postmastectomy radiotherapy: then and now. Oncology (Huntingt) 11 :213-239, 1997. Arriagada R, Rutqvist LE, Mattsson A, et al: Adequate locoregional treatment for early breast cancer may prevent secondary dissemination. J Clin Oncol13:2869-2878, 1995. Overgaard M, Hansen PS, Overgaard J, et al: Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. N Eng} J Med 337:949-955, 1997. Ragaz J, Jackson SM, Le N, et al: Adjuvant radiotherapy and chemotherapy in node-positive premenopausal women with breast cancer.

Elevating the breast prevents subfascial or intrapectoral injection. For those cancers diagnosed with excisional biopsy, injection should be into the wall of the biopsy cavity and surrounding tissue; dye will not translocate into the lymphatics if injected into a seroma-filled biopsy cavity. If a lumpectomy is being performed for a nonpalpable carcinoma, then the dye injection is made at the tip of the localizing wire, or through the localizing needle. Up to 5 cc of dye is used, with less volume, about 3 cc, for lesions closer to the axilla.

53. 54. 55. 56. 57. 58. 59. 60. 19 Rimm EB, Willett WC, Hu FB, et al. Folate and vitamin B6 from diet and supplements in relation to the risk of coronary heart disease among women. JAMA 1998; 279:359. Bines J, Oleske DM, Cobleigh MA. Ovarian function in premenopausal women treated with adjuvant chemotherapy for breast cancer. J Clin Onco11996; 14:1718. Mansour EG, Gray R, Shatila AH, et al. Efficacy of adjuvant chemotherapy in high-risk node-negative breast cancer. N Engl J Med 1989; 320:485 The Ludwig Breast Cancer Study Group.

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