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In other instances, benign reactive lymphoid hyperplasia of the iris can occur as a localized nodular tumor, simulating an iris melanoma or a metastatic tumor (SHIELDS et al. 1981). Ciliary body involvement occurs rarely, if ever, as an isolated entity, but rather occurs as a part of panuveal affection. Posterior uveal involvement is characterized by a diffuse or nodular amelanotic thickening of the choroid. In cases with posterior uveal involvement, the finding of an associated salmon pink conjunctival mass in the same eye facilitates the diagnosis and provides accessible tissue for biopsy confirmation.
It may have a fairly distinct margin or it may blend imperceptibly into the adjacent choroid. Choroidal nevi can have several cytologic variations, including polyhedral, spindle, fusiform, or balloon cells (SHIELDS 1983). Malignant melanomas of the ciliary body and choroid (posterior uvea) differ from melanomas of the iris in several respects. They usually produce more profound symptoms, are larger at the time of clinical recognition, are composed of more malignant cell types, and carry a worse prognosis (SHIELDS 1977).
Summary .................................. References ................................ 31 31 31 32 32 33 33 34 35 41 41 41 The symptoms and signs of MMU are related to the site of origin and the size of the tumor. The most frequently observed symptoms, in order of their occurrence, are: blurred vision, partial subjective loss of vision, ocular pain, amaurosis, and photopsia (FITTERMAN and McLEAN 1963).